Metastatic papillary thyroid carcinoma of the mandible

Posted By : admin

A 68-year-old man with a history of painless swelling in the right side of the mandible and a medical history of thyroidectomy 3 years ago . After that, he received suppression therapy with levothyroxine. One year later, follow-up in the whole body scan  showed no evidence of residual thyroid tissue in thyroid bed and negative for local and distant metastasis.On the second year after thyroidectomy, he complained of swelling

Microscopic examination reveals papillary thyroid carcinoma with multiple branching and true papillae (a). Papillary thyroid carcinoma with bone trabeculae, filtration and destruction (b). Branching papillae lined by cuboidal cells with overlapping nuclei and finely dispersed ground glass chromatin “Orphan Annie nuclei”.

Posted By : admin

Microscopic examination reveals papillary thyroid carcinoma with multiple branching and true papillae (a). Papillary thyroid carcinoma with bone trabeculae, filtration and destruction (b). Branching papillae lined by cuboidal cells with overlapping nuclei and finely dispersed ground glass chromatin “Orphan Annie nuclei”.